We are pleased to announce a new fellowship sponsored by UCSF and Genentech, and focused on regulatory science. In the past decade, a plethora of new healthcare products have been developed, including innovative drugs and biologics, genome and cell-based therapies, mobile health products and implantable devices. Corresponding to the surge in these innovative products, there has been a scarcity of well-trained individuals to expertly develop and evaluate them for safe and effective use. Importantly, there is a new need for individuals who have computational training to apply their skills to the development of drugs, biologics, and medical diagnostics. The educational mission of UCSF in regulatory science is to train a new generation of scientists by providing opportunities to broaden their knowledge about tools, methods, and standards to support regulatory science and medical product development. The UCSF/Genentech postdoctoral fellowship is an experiential program that will provide the most outstanding postdocs with unique immersion experiences in regulatory science research and drug development in areas such as Clinical Pharmacology and Pharmacometrics.
Our objective is that the fellow should have a sufficient foundation and breadth in his/her training to engage in and serve as an ambassador for regulatory science research and education. The fellow will receive a monthly stipend commensurate with education level and experience. The fellow will spend the first year at UCSF, and the second year, when projects are available, the fellow will have an opportunity to train at the FDA. This period of time is flexible, from 3 to 12 months. At the end of two years, the fellow will complete an additional year (after completion of the academic and FDA rotations) at Genentech, Inc. The anticipated start date of the first year fellowship in academia will be on or around August 1, 2020. The fellowship components are:
Research and Training at UCSF (~1 year)
During the first year, the fellow is expected to spend at least 90% of his/her time on a scientific research project. The research project will either extend an existing project or will be an entirely new one-year project. In addition to research, the fellow will be expected to complete UCSF-Stanford CERSI courses focusing on regulatory science and drug development and actively participate in UCSF-Stanford CERSI scientific seminars and symposia. Furthermore, the fellow will take part in regularly scheduled networking and mentoring events.
Immersion Experience at FDA (3-12 months)
During the second year, the fellow, under the mentorship of faculty, will seek training opportunities at the FDA through FDA funding mechanisms such as ORISE. The fellow will be paired with a mentor at the FDA and will work alongside clinicians, engineers, or other scientists in regulatory science research with a focus in Clinical Pharmacology and/or Pharmacometrics. The fellow will either continue his/her research project or will be involved in a new project. Research projects interests will be discussed with the fellow during his/her first year. The fellow will have an opportunity to attend seminars and workshops held at the FDA augmenting the fellow’s learning experience about different aspects of regulatory science and drug development. Furthermore, the fellow will be required to attend an annual UCSF-Stanford CERSI symposium in regulatory science.
Immersion Experience in Industry (1 year)
At the end of two years, the fellow will complete an additional year (after completion of the academic and FDA rotations) at Genentech, Inc. This year will complement and extend his/her training in regulatory science, drug development, Clinical Pharmacology, and Pharmacometrics. The fellow will be assigned a mentor at Genentech, Inc. and will work alongside scientists in the Department of Clinical Pharmacology at Genentech while continuing to be mentored by his/her academic faculty. The mentors will help the fellow design the research project. The fellow will be required to attend an annual UCSF-Stanford CERSI symposium in regulatory science.
Statement of Completion and Employment
Fellows will receive a document certifying their participation in the regulatory science fellowship upon completion of all training components. Immersive experiences in academia and at the FDA do not guarantee job placements.
Applicants must hold a PhD-level degree in pharmaceutical sciences, chemical and biomedical engineering, applied mathematics, or biomedical sciences or another related field, or hold a PharmD degree. Preferably the candidate has experience of mathematical modeling and simulation in pharmacology or biology (e.g. population PK/PD modeling, PBPK, quantitative systems pharmacology, biology) or experience in transporter biology. The candidate must have an excellent record of achievement. Due to the fact that the Fellow will perform work at the FDA, all candidates must be a U.S. citizen or otherwise meet the ORISE Non-U.S. Citizen Requirements (https://orise.orau.gov/fda/applicants/default.html#immigrant). If the Fellow is not approved for a rotation at FDA, intense didactic courses and other training in FDA regulatory sciences will be arranged during the first year training at UCSF. Applicants cannot be current FDA employees, contractors, or fellows.
Applicants are to submit items 1-6 of the required documents in the order listed below as a single PDF via email by Monday, June 15, 2020 to Lawrence.Lin@ucsf.edu. The PDF filename should follow this format: “LastName_UCSF/Genentech Fellowship Application.pdf”.
The following documents are required for a complete application:
Applications will be reviewed by UCSF faculty and Genentech scientists.
The UCSF/Genentech postdoctoral fellowship in regulatory science is supported in part by Genentech, Inc.
After 20 years of NIH funding, the Pharmacogenomics Research Network (PGRN) is transitioning to an independent, nonprofit scientific society, and we are inviting all interested individuals to sign up to become a member of the new PGRN! The independent scientific society will continue many of the functions of the current PGRN, and we encourage you to join today to stay involved. Benefits of joining the new PGRN include:
Special membership rates are available for trainees, multi-year memberships, early sign ups and those from developing countries. In addition, take advantage of the opportunity to be listed on the PGRN website as a founding member if you choose that option during signup.
The College of Pharmacy in Dalhousie’s Faculty of Health invites applications from qualified candidates for a full-time, tenure stream faculty position at either the Assistant or Associate Professor level, depending on the candidate. Exceptional cases at the Professor level may be considered. The anticipated start date on or before January 1, 2021.
Dalhousie University is comprised of 6,000 faculty and staff amongst its 13 faculties. Current enrollment is 18,500 graduate and undergraduate students. As the largest university in the Maritimes and a member of Canada’s U15 research-intensive university group, Dal is an influential driver of the region’s intellectual, social and economic development.
The Faculty of Health’s faculty, staff and students are committed to improving the well-being of individuals, families, communities and populations through diverse health programming, collaborative research and strong community partnerships. The Faculty of Health is one of the largest faculties at Dalhousie, comprised of eight schools, one college and one program, more than 200 faculty members, 80 staff members and over 3,000 students. With the most programmatically diverse health faculty in Canada, our students are exposed to a broad range of health topics and learning experiences.
The College of Pharmacy’s mission is to enhance health and wellness through pharmaceutical education, research and community service. Through our work, we support the conscientious use of medications in society. The College of Pharmacy offers an entry to practice BSc Pharm (last graduating class 2023), an entry to practice PharmD (enrollment begins September 2020), and an MSc in Pharmaceutical Science. Supervision of PhD students is available through the PhD in Health and Interdisciplinary PhD programs or through cross-appointment to other Departments.
The successful candidate will hold a PhD or equivalent degree (e.g. a postgraduate PharmD or other postgraduate degree with a research component) and postdoctoral experience (with a minimum of 2 years preferred) with demonstrated expertise in pharmacogenomics. Evidence of scholarly contributions to pharmacogenomics is required. Expertise of the candidate must be supported by an excellent scientific publication record and/or grant capture commensurate with level of experience and a fundable research plan. The incumbent will have demonstrated ability or potential for excellence in undergraduate and graduate teaching in pharmacogenomics and pharmacokinetic topics that complement our existing core Pharmaceutical Sciences and Pharmacy Practice teaching programs, as well as excellent oral and written communication skills.
The successful candidate is expected to secure extramural research funding, including national tri-council funding and lead an innovative and collaborative research program aimed at applying their expertise to drug discovery, pharmacokinetics and pharmacodynamics and/or the implementation of pharmacogenomics in pharmacy practice with the ultimate goal of improving medication use. This position will complement the College’s core research strengths in Pharmacology and Pharmacokinetics, Pharmaceutics and Biopharmaceutics and Medicinal Chemistry and will contribute to Faculty’s strategy to achieve a critical mass of strong faculty in our focused areas of research.
The successful candidate will be required to teach undergraduate/graduate students as well as mentor and supervise graduate students. Teaching assignments will include teaching in the BSc Pharm/PharmD problem-based learning curricula and didactic courses and MSc Pharmaceutical Sciences courses to reflect the expertise of the successful candidate within the needs of the College. The candidate is expected to become an active and engaged member of the College, Faculty and University. Activities at local, national and international levels are expected to promote continuous improvement in research, teaching and learning at Dalhousie.
Applicants must submit a cover letter (maximum 2 pages) describing their qualifications and experience; a Curriculum Vitae including a list of publications; and a statement of teaching experience, interests and teaching philosophy (maximum 1 page). Applicants must also submit an original, innovative 5-year research plan (maximum 3 pages) that includes a summary of objectives, methodological approaches, potential partnerships and collaborators, target funding agencies and how the proposed research may fit within the Faculty’s core research strengths (https://www.dal.ca/faculty/health/research/our-research.html). Please submit directly to PeopleAdmin. Review of applications will begin on May 15, 2020 and continue until the position is filled.
This position is subject to final budgetary approval. All qualified candidates are encouraged to apply; however, Canadians and permanent residents will be given priority.
Dalhousie University is committed to fostering a collegial culture grounded in diversity and inclusiveness. The university encourages applications from Indigenous persons, persons with a disability, racially visible persons, women, persons of a minority sexual orientation and/or gender identity, and all candidates who would contribute to the diversity of our community. For more information, please visit https://www.dal.ca/hiringfordiversity.
The Department of Pharmacology at Dalhousie University is seeking to fill a tenure-stream position with an anticipated start date of January 2021 (negotiable).
The successful applicant will have a PhD, or equivalent, and postdoctoral experience (at least two years
preferred). Candidates should have a demonstrated record of, or potential for, high-quality research,
teaching, and administrative service commensurate with their career stage. The successful candidate
will be expected to develop and maintain a strong externally funded research program and to teach at
the undergraduate and graduate levels. The successful candidate will have expertise in pharmacology
and genomics, preferably in research areas such as the integration of genomics and bioinformatics into personalized medicine, pharmacogenomics, application of genomics in clinical pharmacology and effects of genetic variability on drug efficacy, pharmacokinetics or adverse drug reactions. The Department of Pharmacology maintains a strong research profile across a wide range of health-related fields.
Information on the research activities of the Department of Pharmacology can be found at
Dalhousie University provides exceptional opportunities for translational genomics research. Both the
CIHR Institutes of Genetics and Genome Atlantic are housed in close proximity to the Department of
Pharmacology. Applicants should indicate their research alignment with genomics, which is one of the
strategic areas within the Faculty of Medicine and in particular, the potential for research interactions
with the Centre for Genomics Enhanced Medicine https://www.cgem.ca and the Centre for Comparative Genomics & Evolutionary Bioinformatics http://cgeb.dal.ca .
A complete application requires:
1. cover letter;
2. curriculum vitae;
3. research statement/plan (addressing past, current and future research); and
4. teaching dossier
Two academic references will be requested for short-listed candidates.
Interested candidates, please apply via PeopleAdmin http://dal.peopleadmin.ca/postings/2899 by
April 15, 2020.
All qualified candidates are encouraged to apply; however, Canadians and permanent residents will be
given priority. Dalhousie University is committed to fostering a collegial culture grounded in diversity and inclusiveness. The university encourages applications from Indigenous persons, persons with a
disability, racially visible persons, women, persons of a minority sexual orientation and/or gender identity, and all candidates who would contribute to the diversity of our community. For more information, please visit www.dal.ca/hiringfordiversity.
The College of Pharmacy at the University of Kentucky is recruiting in the area of Genetics/Genomics/Pharmacogenomics of Immune Function in Disease for a 12-month, tenure-track appointment at the Assistant Professor level with an anticipated start date of Fall 2020, although exceptional candidates at any level can also be considered. We seek candidates who can help grow our new program in the modulation of immune function as it impacts disease with expertise in relating genotype to phenotypic response, as well as in genetic approaches to the diagnosis and prediction of disease, or the discovery, development and evaluation of novel therapeutic interventions. Special consideration will be given to candidates whose research interests complement the College’s signature research themes including substance use disorders, cancer, neurological and metabolic disorders, and infectious diseases.
All candidates must possess a PharmD, PhD, PharmD/PhD, MD/PhD or other advanced degree(s) in pharmaceutical sciences or a related discipline and a record of scholarship and research productivity. Selected candidates will be expected to develop and maintain an extramurally-supported research program, engage in the College of Pharmacy graduate training program, and contribute significantly to providing the conceptual and practical skills for the next generation of professional Pharm.D. students to become leaders in the field of pharmacy practice.
St. Jude Children’s Research Hospital is seeking an innovative and strategic leader to serve as the Chair of the Department of Pharmaceutical Sciences. The successful candidate will have a strong track record of scholarship in pharmaceutical sciences as well as demonstrated leadership experience. Work experience in a cancer research setting is highly desirable as is the ability to effectively foster a supportive and collaborative workplace dedicated to cutting-edge research and optimal clinical care. Additional expectations include strong communications skills, financial acumen to oversee the departmental budget, ability to secure extramural funding and dedication to faculty mentorship and career development.
The Department of Pharmaceutical Sciences plays a central role in advancing the institutional mission of finding cures and saving children through research and treatment for pediatric cancer and other life-threatening diseases. The department has historically integrated both pharmaceutical sciences (with a primary mission of research), and pharmaceutical services (with a primary mission of clinical care), with a goal of rapidly translating research findings into clinical care. Its primary goals are to discover the biological basis for inter-individual differences in response to medications, to translate research findings to improve treatment outcomes, and to provide the best and most comprehensive pharmaceutical care for St. Jude patients. Department faculty are internationally recognized for their research in fundamental and clinical pharmacology, pharmacokinetics, pharmacodynamics, pharmacogenomics, pediatric therapeutics, and medication safety. The department includes Pharmaceutical Services, the CAP/CLIA-accredited Clinical Pharmacokinetics and Therapeutic Drug Monitoring Laboratory for St. Jude, as well as the Comprehensive Cancer Center’s Pharmacokinetics Shared Resource.
The department and institution provide a collaborative environment designed to foster transdisciplinary work in basic, translational and clinical sciences. The department hosts multiple regular multidisciplinary meetings and webinars, and its faculty, staff, and trainees are highly collaborative with other clinical, translational, and basic science research departments at St. Jude, as well as at the University of Tennessee Colleges of Medicine and Pharmacy. The department supports education and training of professional students, graduate students, clinical fellows, PGY2 pharmacy residents, and post-doctoral fellows. Pharmaceutical Sciences Department faculty, staff, and trainees work closely with each other; with collaborators in other departments at St. Jude; and with colleagues around the world to advance research and cures for pediatric patients. Additional details about the department can be found: https://www.stjude.org/research/departments-divisions/pharmaceutical-sciences.html
Applications and nominations should be sent to the Search Committee Chair via Melissa Jones at firstname.lastname@example.org.
The PGRN Hub congratulates the 2019 PGRN Poster Session at ASHG Trainee Award Winners.
Trainee Award Winners
Genetic basis of pharmacokinetic variability in African Americans
Tanima De, Northwestern University
Massively parallel functional profiling of CYP2C9 variants using a yeast activity assay
Clara Amorosi, University of Washington
A Pilot Clinical Trial of a CYP2D6 Genotype-Guided Pain Management Strategy in Patients Undergoing Total Joint Arthroplasty
Cameron D. Thomas, University of Florida
Pharmacogenomics of Docetaxel Response in Prostate Cancer: A Precision Medicine Initiative
Abhinav Grover, University of California, Irvine
Transcriptome-wide association study of anthracycline-induced cardiotoxicity in pediatric cancer patients
Erika N. Scott, University of British Columbia
HLA Haplotype DRB1*07:01-DQA1*02:01-DQB1*02:02 Predicts Pegaspargase Hypersensitivity
Yiwei Liu, St. Jude Children's Research Hospital
Quantitative proteomic profile of Caribbean Hispanics with high on-treatment platelet reactivity (HTPR) to clopidogrel
Ednalise Santiago, University of Puerto Rico - Medical Sciences Campus
The Department of Pharmaceutical Sciences and Experimental Therapeutics invites applications for a twelve-month, tenure track Assistant/Associate Professor with research interests in Pharmacogenomics, to join the Division of Pharmaceutics and Translational Therapeutics. The duties of this position include developing and/or maintaining an active research program in genomic science and methodology, including development of collaborations to integrate genomic/genetic/epigenetic science into practice-based and clinical research, as well as advancing knowledge in pharmacogenomic science. In addition to scholarly pursuits, the candidate will be expected to contribute to excellence in the teaching programs of the College of Pharmacy, in mentoring graduate students and post-doctoral scholars, and in providing service to the department, college, university and scientific community.
The Division of Pharmaceutics and Translational Therapeutics consists of faculty members with expertise in pharmacokinetics, pharmacodynamics, experimental therapeutics, biomaterials, pharmaceutics, pharmaceutical chemistry and drug delivery. The Division is home to two Ph.D. subtracks, one focused in Pharmaceutics and the other in the Clinical Pharmaceutical Sciences; more than 50 graduate students, post-doctoral fellows and visiting scientists participate in the educational and research programs within the division, and the College of Pharmacy enrolls over 400 students in the Pharm.D. professional degree program.
The PGRN Poster Session & Reception will be held on October 17th, 2019 during the 2019 ASHG Annual Meeting in Houston . Abstract poster submission deadline is August 31st, 2019 - authors will be notified of their submission's status by September 15th, 2019.
The Hub team